Treatment Options | Johns Hopkins Aramco Healthcare
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When it comes to treatment, our goal is to provide care that's as seamless, advanced, and patient-friendly as possible. As our knowledge of breast cancer increases, so does our ability to tailor treatment to individual patients based on tumor characteristics, genetics, family history, and personal preferences.

Depending on your cancer stage, the characteristics of your tumor, as well as your individual needs and expectations, our specialists will create a personalized treatment plan for you.

Breast-Conserving Surgery (Lumpectomy)

For many patients, breast-conserving surgery removes the tumor while preserving most of the breast. Our surgeons use advanced oncoplastic techniques to achieve the best cosmetic outcomes.

Benefits:

  • Preserves breast appearance
  • Equivalent survival to mastectomy for appropriate candidates
  • Shorter recovery time
  • Less invasive

Mastectomy

When mastectomy is recommended or chosen, we offer several options:

  • Simple Mastectomy - Removal of breast tissue
  • Skin-Sparing Mastectomy - Preserves breast skin for reconstruction
  • Nipple-Sparing Mastectomy - Preserves nipple and areola when appropriate
  • Bilateral Mastectomy - Both breasts removed (risk reduction or patient preference)

Lymph Node Surgery

  • Sentinel Lymph Node Biopsy - Minimally invasive sampling of first draining lymph nodes
  • Axillary Lymph Node Dissection - When more extensive lymph node removal is needed

Breast Reconstruction

We offer immediate and delayed reconstruction options to help you feel whole again:

Implant-Based Reconstruction:

  • Tissue expanders followed by permanent implants
  • Direct-to-implant reconstruction
  • Latest implant technologies

Autologous Tissue Reconstruction:

  • DIEP flap (using abdominal tissue)
  • Latissimus dorsi flap
  • Other advanced flap techniques

Oncoplastic Surgery:

  • Tissue rearrangement techniques
  • Volume replacement procedures
  • Symmetry procedures

Chemotherapy

Our medical oncologists are experts in administering and managing chemotherapy regimens:

  • Neoadjuvant chemotherapy (before surgery)
  • Adjuvant chemotherapy (after surgery)
  • Treatment for metastatic disease
  • Personalized regimens based on tumor characteristics

Hormonal Therapy (Endocrine Therapy)

For hormone receptor-positive breast cancers:

  • Tamoxifen
  • Aromatase inhibitors (anastrozole, letrozole, exemestane)
  • Ovarian suppression (for premenopausal women)
  • CDK4/6 inhibitors (for metastatic disease)

Targeted Therapy

For HER2-positive breast cancers:

  • Trastuzumab (Herceptin)
  • Pertuzumab (Perjeta)
  • T-DM1 (Kadcyla)
  • Neratinib (Nerlynx)
  • Other novel HER2-targeted agents

Immunotherapy

For triple-negative breast cancer:

  • Pembrolizumab (Keytruda)
  • Atezolizumab (Tecentriq)
  • Combination with chemotherapy

Precision Medicine

Genomic testing helps guide treatment decisions:

  • Oncotype DX for early-stage hormone-positive cancer
  • Foundation One for advanced cancers
  • Clinical trial matching based on genetic profile

Our radiation oncologists provide personalized, patient-centered radiation treatment:

Techniques:

  • Whole Breast Radiation - Standard treatment after lumpectomy
  • Partial Breast Irradiation - Accelerated treatment targeting tumor bed
  • Hypofractionated Radiation - Shorter course with equivalent outcomes
  • Intraoperative Radiation Therapy (IORT) - Single-dose radiation during surgery
  • Chest Wall Radiation - After mastectomy when indicated
  • Advanced Planning - Techniques to minimize heart and lung exposure

Your Complete Care Team

Treatment is just one part of your comprehensive care at JHAH. Our integrated approach ensures you have access to all the services you need throughout your journey.

Before Treatment Begins Our Diagnosis & Testing services provide the detailed information needed to create your personalized treatment plan, including molecular testing and genetic analysis that guide therapy decisions.

During Treatment Our Support & Survivorship Services help you manage side effects, maintain your quality of life, and connect with others on similar journeys. From nutrition counseling to emotional support, we're here for every aspect of your care.

Specialized Care Options If you have young-onset, hereditary, triple-negative, or metastatic breast cancer, our Specialized Programs offer targeted expertise and advanced treatment protocols designed for your specific situation.

Ongoing Monitoring After treatment, our Prevention & Screening programs provide enhanced surveillance to monitor your health and detect any changes early.

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